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Medications and Pregnancy

Talk with your doctor if you are pregnant and you have taken any medication or are thinking of taking any medication. This includes prescription and over-the-counter medications, as well as dietary or herbal products.

Pregnant women should not stop or start taking any type of medication that they need without first talking with a doctor. Women who are planning to become pregnant should discuss the need for any medication with their doctor before becoming pregnant and ensure they are taking only medications that are necessary.

We know that taking certain medications during pregnancy can cause serious birth defects. Examples are thalidomide (also known as Thalamid®) and isotretinoin (also known as Accutane®).

Such medications should be avoided by all women who are or might become pregnant. While some medications are known to be harmful when taken during pregnancy, the safety of most medications taken by pregnant women has been difficult to determine. The effects depend on many factors, such as:

  • How much medication was taken.

  • When during the pregnancy the medication was taken.

  • Other health conditions a woman might have.

  • Other medications a woman takes.

We do not have enough information about the effects of many medications when they are taken by pregnant women. The U.S. Food and Drug Administration (FDA) regulates medications to ensure their general safety and effectiveness. All prescription and over-the-counter medications are tested to see if they are safe and effective before they become available to the public. Pregnant women usually are not included in these tests because of the possible risks to the unborn baby. As a result, little information is available about the safety of most medications during pregnancy—including those available over the counter—when they first become available. It is important to know that dietary and herbal products also could be harmful to an unborn baby or have other side effects when used during pregnancy.

Pregnant animals sometimes are studied to help identify harmful medications. But animal studies do not always show how medications will work in humans. They might miss some harmful effects that medications have. And, over-the-counter medications and dietary or herbal products are not always tested in animals.

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